OK, I will go to fill in some details.
I am using R26 on windows11. What I said is once I create a abc file, and load it in a c4d scene(just like your image, I successfully load it as an abc object), I cannot write a new version of file to this path unless I close c4d.
So every I want to check the shading of a new abc file, I will follow the step.

1. Close c4d
2. export a new abc file to overwrite the old one
3. Open c4d, waiting for all the plugins that need to connect to the internet

I use houdini to create and export some abc file to c4d.
But I found that when the abc file is loading in c4d, it can not be delete or overwrite?
I have to restart c4d(due to octane render, it is really slow when reopen an existing project).
Is there a script to release the abc file so that I can overwrite it?